Set in a post-apocalyptic world where an outbreak has wiped out most of humanity, The Lust of Us follows the story of a Survivor, tasked with escorting a young girl through a land ravaged by the undead. Along the way, he makes mistakes, but he has the chance to change what was perhaps his biggest mistake. The two must fight infected and hostile human factions, accept their mistakes and discover new feelings, all the while walking through a dangerous world where resources are scarce and survival is uncertain.